The motion of a drop in a rigid surface

The assumptions of a region of slip near a moving contact line (to remove the force singularity) and a constant contact angle are used to obtain the equation for the shape of a thin drop of liquid resting on a rigid plane. Three asymptotic expansions are matched together to obtain an expression for the rate at which the drop spreads. Some cases of sliding motion are also examined. Although the technique is presented here for thin drops only, it can also be applied to drops of arbitrary size

Free surface flows with large slopes: beyond lubrication theory

The description of free surface flows can often be simplified to thin film (or lubrication) equations, when the slopes of the liquid-gas interface are small. Here we present a long wavelength theory that remains fully quantitative for steep interface slopes, by expanding about Stokes flow in a wedge. For small capillary numbers, the variations of the interface slope are slow and can be treated perturbatively. This geometry occurs naturally for flows with contact lines: we quantify the difference with ordinary lubrication theory through a numerical example and analytically recover the full Cox-Voinov asymptotic solution.Comment: 4 pages, 3 figure

An Example of Boundary Layer Formation

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/77560/1/AIAA-1774-282.pd

The chick as an animal model of eye disease

A diverse range of chicken lines harbouring highly-penetrant, spontaneously-occurring mutations with an ocular phenotype have been identified over the past 40 years. These lines serve as models for human monogenic disorders including ocular albinism, retinal dystrophies such as Leber's congenital amaurosis, and coloboma, as well as the common complex traits glaucoma and myopia. Recent technical advances in gene targeting, mapping quantitative trait loci, and phenotypic characterisation of eye phenotypes offer exciting prospects for exploiting chicken genomic resources in fundamental and translational eye research

Mapping the Rehabilitation Interventions of a Community Stroke Team to the Extended International Classification of Functioning, Disability and Health Core Set for Stroke

Purpose: This study aim was to evaluate if the Extended International Classification of Functioning, Disability and Health Core Set for Stroke captured the interventions of a community stroke rehabilitation team situated in a large city in New Zealand. It was proposed that the results would identify the contribution of each discipline, and the gaps and differences in service provision to Māori and non-Māori. Applying the Extended International Classification of Functioning, Disability and Health Core Set for Stroke in this way would also inform whether this core set should be adopted in New Zealand. Method: Interventions were retrospectively extracted from 18 medical records and linked to the International Classification of Functioning, Disability and Health and the Extended International Classification of Functioning, Disability and Health Core Set for Stroke. The frequencies of linked interventions and the health discipline providing the intervention were calculated. Results: Analysis revealed that 98.8% of interventions provided by the rehabilitation team could be linked to the Extended International Classification of Functioning, Disability and Health Core Set for Stroke, with more interventions for body function and structure than for activities and participation, no interventions for emotional concerns and limited interventions for community, social and civic life. Results support previous recommendations for additions to the EICSS. Conclusions: The results support the use of the Extended International Classification of Functioning, Disability and Health Core Set for Stroke in New Zealand, and demonstrates its use as a quality assurance tool that can evaluate the scope and practice of a rehabilitation service

Particle size segregation in granular flow in silos

Segregation and layering of alumina in storage silos are investigated, with a view to predicting output quality versus time, given known variations in input quality on emplacement. A variety of experiments were conducted, existing relevant publications were reviewed, and the basis for an algorithm for predicting the effect of withdrawing from a central flowing region, in combination with variations in quality due to geometric, layering and segregation effects, is described in this report

Mutation in the guanine nucleotide-binding protein beta-3 causes retinal degeneration and embryonic mortality in chickens

PURPOSE. To identify the gene defect that causes blindness and the predisposition to embryonic death in the retinopathy globe enlarged (rge) chicken. METHODS. Linkage analysis, with previously uncharacterized microsatellite markers from chicken chromosome 1, was performed on 138 progeny of an rge/+ and an rge/rge cross, and candidate genes were sequenced. RESULTS. The rge locus was refined and the gene for guanine nucleotide-binding protein β-3 (GNB3), which encodes a cone transducin β subunit, was found to have a 3-bp deletion (D153del) that segregated with the rge phenotype. This mutation deleted a highly conserved aspartic acid residue in the third of seven WD domains in GNB3. In silico modeling suggested that this mutation destabilized the protein. Furthermore, a 70% reduction was found in immunoreactivity to anti-GNB3 in the rge-affected retina. CONCLUSIONS. These findings implicate the β-subunit of cone transducin as the defective protein underlying the rge phenotype. Furthermore, GNB3 is ubiquitously expressed, and the c.825C→T GNB3 splicing variant (MIM 139130) has been associated with hypertension, obesity, diabetes, low birth weight, coronary heart disease, and stroke in the human population. It therefore seems likely that the defect underlying these human diseases also causes reduced embryonic viability in the rge chicken, making it a powerful model for studying the pathology involved in these associations

NASA PTTI programs: Present and future

Current and future Precise Time and Time Interval (PTTI) programs at the Goddard Space Flight Center (GSFC) and the evolution of frequency and time requirements over past years within the various NASA satellite tracking networks are described. A brief history of the network development is also given